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Spearhead Bio

1 viewer · 30d

Total raised

$1.2M

+$1.2M this year

1 filing since 2026 · latest SAFE filed

Cumulative raised
LAST ROUND
SAFE · $1.2M
ROUNDS
1
INVESTORS
4
FOUNDED
2024
HQ
Saint Louis, MO
SECTOR
Biotech
EMPLOYEES
N/A
30D VIEWERS
1

AI overview

Updated

Spearhead Bio is a Saint Louis, Missouri agricultural biotechnology company spun out of the Donald Danforth Plant Science Center by the Danforth Technology Company in February 2025. It develops native genome engineering tools that make targeted gene insertion in crops far more efficient, addressing a long-standing bottleneck in CRISPR-based plant editing. Its TAHITI (Transposase Assisted Homology Independent Targeted Insertion) platform integrates genes into both transgenic and non-transgenic crops using the plant's own natural DNA. The technology was developed by founder and Chief Scientific Officer Keith Slotkin, PhD, and the company is led by CEO Mike Bielski.

What sets it apart

TAHITI uses the plant's own natural DNA and a transposase-assisted, homology-independent mechanism to insert genes at a target site, sidestepping the low efficiency of homology-directed repair in plants; because no foreign genetic material is required, it can reduce regulatory hurdles and improve consumer acceptance relative to conventional transgenic approaches.

Funding history

1 round
SAFE+1Jun 18, 2026
Form D
+$1.2M$1.2M total

Latest SEC filings

via EDGAR · CIK 0002057359
Form D · Jun 18, 2026NewView on EDGAR

Products

1 tracked

TAHITI (Transposase Assisted Homology Independent Targeted Insertion)

Agricultural genome engineering platform

A native genome engineering platform that enables seamless, targeted insertion of genes into crop genomes — in both transgenic and non-transgenic crops — using the plant's own natural DNA rather than foreign sequence.

  • Transposase-assisted, homology-independent targeted insertion
  • Works in both transgenic and non-transgenic crops
  • Uses the plant's natural DNA, avoiding foreign genetic material
  • Seamless integration at the target site

Links

WebsiteLinkedInSEC EDGAR filings