Condensate modulator (c-mod) pipeline
Clinical-stage small-molecule therapeuticsA portfolio of small-molecule condensate modulators discovered on the ERSAi platform, led by DPTX3186, a beta-catenin condensate modulator in Phase 1/2 for gastric cancer with FDA fast track and orphan drug designations, alongside an oral MYC modulator enrolling patients in solid tumors and a TDP-43 development candidate for ALS.
- ERSAi discovery platform combining high-resolution condensate biology, chemistry, proprietary datasets, and AI
- DPTX3186, a beta-catenin condensate modulator in Phase 1/2 for gastric cancer, with FDA fast track and orphan drug designation and first patient dosed in early 2026
- Oral MYC condensate modulator in Phase 1/2, enrolling patients in solid tumors
- TDP-43 condensate modulator development candidate for ALS and related neurodegenerative diseases