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Aminex Therapeutics

2 viewers · 30d

Total raised

$15.1M

1 filing since 2022 · latest Equity filed

Cumulative raised
LAST ROUND
Equity · $15.1M
ROUNDS
1
INVESTORS
162
FOUNDED
N/A
HQ
Kenmore, WA
SECTOR
Biotech
EMPLOYEES
N/A
30D VIEWERS
2

AI overview

Updated

Aminex Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing novel immuno-oncology therapies. Their primary strategy is to overcome immune system suppression within the tumor microenvironment by targeting and depleting polyamines, thereby enabling the body's own immune system to attack cancer cells.

What sets it apart

The company is a pioneer in developing a therapeutic approach based on polyamine depletion, which addresses two key immune suppressors—polyamines and myeloid-derived suppressor cells (MDSCs)—with a single combination therapy.

Funding history

1 round
EquityOct 25, 2022
Form D
+$15.1M$15.1M total

Latest SEC filings

via EDGAR · CIK 0001613386
Form D · Oct 25, 2022View on EDGAR

Products

1 tracked

AMXT 1501 + DFMO Combination Therapy

Cancer Immunotherapy

The flagship product is an oral, small molecule therapy that combines AMXT 1501, a proprietary polyamine uptake inhibitor, with DFMO (eflornithine), a polyamine synthesis inhibitor. This dual-agent approach works synergistically to significantly lower polyamine levels in cancer cells and the surrounding tumor microenvironment, which in turn suppresses myeloid-derived suppressor cells (MDSCs) and restores the innate immune system's ability to fight solid tumors.

  • Oral, small molecule therapy
  • Dual-agent combination of AMXT 1501 and DFMO
  • Inhibits both polyamine uptake and synthesis
  • Suppresses myeloid-derived suppressor cells (MDSCs)